Publications

Title Author Year Publication type
A Causal Roadmap for Generating High-Quality Real-World Evidence Lauren E Dang , Susan Gruber , Hana Lee , Issa J Dahabreh , Elizabeth A Stuart , Brian D Williamson , Richard Wyss , Iván Dí 2023 Journal Article
Who is most at risk of dying if infected with SARS-CoV-2? A mortality risk factor analysis using machine learning of patients with COVID-19 over time: a large population-based cohort study in Mexico Lauren D Liao, Alan E Hubbard, Juan Pablo Gutierrez, Arturo Juárez-Flores, Kendall Kikkawa, Ronit Gupta, Yana Yarmolich, Iván de Jesús Ascencio-Montiel, Stefano M Bertozzi 2023 Journal Article
An Application of the Causal Roadmap in Two Safety Monitoring Case Studies: Causal Inference and Outcome Prediction using Electronic Health Record Data Brian D Williamson,Richard Wyss, Elizabeth A Stuart, Lauren E Dang, Andrew N Mertens, Romain S Neugebauer, Andrew Wilson, Susan Gruber 2023 Journal Article
Causes and Consequences of Child Growth Faltering in Low-resource settings Andrew Mertens, Jade Benjamin-Chung, John M. Colford Jr, Jeremy Coyle, Mark J. van der Laan, Alan E. Hubbard, Sonali Rosete, Ivana Malenica, Nima Hejazi, Oleg Sofrygin, Wilson Cai, Haodong Li, etc. 2023 Journal Article
Conformal Meta-learners for Predictive Inference of Individual Treatment Effects Mark van der Laan; Ahmed M. Alaa; Zaid Ahmad 2023 Journal Article
Blurring cluster randomized trials and observational studies: Two-Stage TMLE for subsampling, missingness, and few independent units Joshua R Nugent; Carina Marquez; Edwin D Charlebois; Rachel Abbott; Laura Balzer 2023 Journal Article
Targeted Learning: Toward a Future Informed by Real-World Evidence Mark van der Laan; Rachael Phillips; Susan Gruber; Martin Ho; John Concato; Hana Lee 2023 Journal Article
Targeted Learning Handbook: Causal Machine Learning and Inference in the tlverse R Software Ecosystem Jeremy Coyle, Mark van der Laan, Alan Hubbard, Rachael Phillips, Ivana Malenica, Nima Hejazi 2022 Book
The optimal dynamic treatment rule superlearner: considerations, performance, and application to criminal justice interventions Montoya LM, van der Laan MJ, Luedtke AR, Skeem JL, Coyle JR, Petersen ML. 2022 Journal Article
Estimators for the value of the optimal dynamic treatment rule with application to criminal justice interventions Montoya LM, van der Laan MJ, Skeem JL, Petersen ML. 2022 Journal Article
Machine learning to identify persons at high-risk of HIV acquisition in rural Kenya and Uganda Balzer LB, Havlir DV, Kamya MR, Chamie G, Charlebois ED, Clark TD, Koss CA, Kwarisiima D, Ayieko J, Sang N, Kabami J, Atukunda M, Jain V, Camlin CS, Cohen CR, Bukusi EA, van der Laan M, Petersen ML. 2020 Journal Article
Dynamic Impact of Transfusion Ratios on Outcomes in Severely Injured Patients: Targeted Machine Learning Analysis of the Pragmatic, Randomized Optimal Platelet and Plasma Ratios Randomized Clinical Trial Nguyen, M.; Pirracchio, R.; Kornblith, L. Z.; Callcut, R.; Fox, E. E; Wade, C. E.; Schreiber, M.; Holcomb, J. B.; Coyle, J.; Cohen, M.; Hubbard, A. E. 2020 Journal Article
Countering the Curse of Dimensionality: Exploring Data-generating Mechanisms Through Participant Observation and Mechanistic Modeling; Epidemiology Hubbard, Alan; Trostle, James; Trostle, James; Cangemi, Ivan; Eisenberg, Joseph N. S 2020 Journal Article
Super learner analysis of real-time electronically monitored adherence to antiretroviral therapy under constrained optimization and comparison to non-differentiated care approaches for persons living with HIV in rural Uganda †Benitez AE, Musinguzi N, Bangsberg DR, Bwana MB, Muzoora C, Hunt PW, Martin JN, Haberer JE, Petersen ML 2020 Journal Article
Application of machine learning methodology to assess the performance of DIABETIMSS program for patients with type 2 diabetes in family medicine clinics in Mexico Yue You; Svetlana V. Doubova; Diana Pinto-Masis; Ricardo Pérez-Cuevas; Víctor Hugo Borja-Aburto; Alan Hubbard 2019 Journal Article
Improved Small-Sample Estimation of Nonlinear Cross-Validated Prediction Metrics Benkeser D, Petersen M & van der Laan MJ 2019 Journal Article
Big data and targeted machine learning in action to assist medical decision in the ICU; Anesthesia Critical Care \& Pain Medicine Pirracchio, Romain; Cohen, Mitchell J.; Malenica, Ivana; Cohen, Jonathan; Chambaz, Antoine; Cannesson, Maxime; Lee, Christine; Resche-Rigon, Matthieu; Hubbard, Alan E. 2019 Journal Article
Estimation of direct causal effects Petersen ML, Sinisi SE, van der Laan MJ 2019 Journal Article
Mining with Inference: Data Adaptive Target Parameters Hubbard, Alan E.; van der Laan, Mark J. 2019 Journal Article
Causal inference when counterfactuals depend on the proportion of all subjects exposed §Miles CH,; Petersen M,; van der Laan MJ 2019 Journal Article
HIV Testing and Treatment with the Use of a Community Health Approach in Rural Africa Havlir DV, Balzer LB, Charlebois ED, Clark TD, Kwarisiima D, Ayieko J, Kabami J, Sang N, Liegler T, Chamie G, Camlin CS, Jain V, Kadede K, Atukunda M, Ruel T, Shade SB, Ssemmondo E, Byonanebye DM, Mwangwa F, Owaraganise A, Olilo W, Black D, Snyman K,; Burger R, Getahun M, Achando J, Awuonda B, Nakato H, Kironde J, Okiror S, Thirumurthy H, Koss C, Brown L, Marquez C, Schwab J, Lavoy G, Plenty A, Mugoma Wafula E, Omanya P, Chen YH, Rooney JF, Bacon M, van der Laan M, Cohen CR, Bukusi E, Kamya MR,; Petersen M. 2019 Journal Article
Double Robust Efficient Estimators of Longitudinal Treatment Effects: Comparative Performance in Simulations and a Case Study Tran L, Yiannoutsos C, Wools-Kaloustian K, Siika A, van der Laan M, Petersen M. 2019 Journal Article
Statistical inference for the mean outcome under a possibly non-unique optimal treatment strategy A. R. Luedtke; M. J. van der Laan 2019 Journal Article
Optimal Individualized Treatments in Resource-Limited Settings A. Luedtke; M. van der Laan 2018 Journal Article
A new approach to hierarchical data analysis: Targeted maximum likelihood estimation for the causal effect of a cluster-level exposure †Balzer L,; Zheng W,; van der Laan M,; Petersen M 2018 Journal Article
Targeted Learning in Data Science: Causal Inference for Complex Longitudinal Sherri Rose; Mark van der Laan 2018 Book
Targeted Learning in Data Science - Causal Inference for Complex Longitudinal Studies M.J. van der Laan; S. Rose 2018 Book
Doubly robust nonparametric inference on the average treatment effect D. Benkeser; P. Gilbert; M.J. van der Laan; M. Carone 2017 Journal Article
Longitudinal Mediation Analysis with Time-varying Mediators and Exposures, with Application to Survival Outcomes W. Zheng; M. van der Laan 2017 Journal Article
Association of implementation of a universal testing and treatment intervention with HIV diagnosis, receipt of antiretroviral therapy, and HIV viral suppression among adults in East Africa Petersen M,; Balzer L,; Kwarsiima D,; Sang N5,; Chamie G2,; Ayieko J,; Kabami J,; Owaraganise A,; Liegler T,; Mwangwa F,; Kadede K,; Jain, V,; Plenty A,; Brown L,; Lavoy G,; Schwab J,; Black D,; van der Laan M,; Bukusi E,; Cohen C,; Clark T,; Charlebois E,; Kamya M,; Havlir D 2017 Journal Article
Petersen M. Constrained binary classification using ensemble learning: an application to cost-efficient targeted PrEP strategies †Zheng W; §Balzer L; van der Laan M 2017 Journal Article
Big Data, Small Sample: Edgeworth Expansions Provide a Cautionary Tale Gerlovina, Inna; van der Laan, Mark J; Hubbard, Alan 2017 Journal Article
Evaluating the Impact of a HIV Low-Risk Express Care Task-Shifting Program: A Case Study of the Targeted Learning Roadmap. †Tran L; Yiannoutsos CT; Musick BS; Wools-Kaloustian K; Siika A; Kimaiyo S; van der Laan M; Petersen M 2016 Journal Article
Adaptive pre-specification in randomized trials with and without pair-matching Balzer, LB; van der Laan, MJ; Petersen, ML; SEARCH Collaboration 2016 Journal Article
Adaptive pre-specification in randomized trials with and without pair-matching: SEARCH Collaboration L.B. Balzer; M.L. Petersen; M.J. van der Laan 2016 Journal Article
Statistical Inference for Data Adaptive Target Parameters Hubbard, A.; Kherad-Pajouh, S.; van der Laan, M. 2016 Journal Article
Targeted estimation and inference for the sample average treatment effect in trials with and without pair matching †Balzer, L; Petersen, M; van der Laan, M; the SEARCH Collaboration 2016 Journal Article
Causal Models and Learning from Data: Integrating Causal Modeling and Statistical Estimation in the Practice of Epidemiology Maya Petersen; Mark van der Laan 2015 Journal Article
Entering the era of data science: Targeted Learning and the Integration of Statistics and Computational Data Analysis M.J. van der Laan; R.J.C.M. Starmans 2014 Journal Article
Targeted learning of the mean outcome under an optimal dynamic treatment rule M. J. van der Laan; A. R. Luedtke 2014 Journal Article
Targeted Maximum Likelihood Estimation for Dynamic and Static Longitudinal Marginal Structural Working Models Petersen M, Schwab J, Gruber S, Blaser N, Schomaker M, van der Laan M. 2014 Journal Article
Effect of breastfeeding on gastrointestinal infection in infants: A targeted maximum likelihood approach for clustered longitudinal data M. E. Schnitzer; M. J. van der Laan; E. E. Moodie; R. W. Platt 2014 Journal Article
Causal models and learning from data: integrating causal modeling and statistical estimation Petersen ML, van der Laan MJ 2014 Journal Article
Causal Inference for a Population of Causally Connected Units M. J. van der Laan 2014 Journal Article
Targeted Learning in real-world comparative effectiveness research with time-varying interventions R. Neugebauer; J. Schmittdiel; M.J. van der Laan 2014 Journal Article
Targeted Minimum Loss-Based Estimation of Causal Effects in Right-Censored Survival Data with Time Dependent Covariates: Warfarin, Stroke, and Death in Atrial Fibrillation J. Brooks; M. J. van der Laan; D.E. Singer; A. S. Go 2013 Journal Article
Time-dependent prediction and evaluation of variable importance using superlearning in high-dimensional clinical data Hubbard, Alan; Munoz, Ivan Diaz; Decker, Anna; Holcomb, John B.; Schreiber, Martin A.; Bulger, Eileen M.; Brasel, Karen J.; Fox, Erin E.; del Junco, Deborah J.; Wade, Charles E.; others 2013 Journal Article
Targeted Minimum Loss Based Estimation of Marginal Structural Working Models M. Petersen; J. Schwab; S. Gruber; N. Blaser; M. Schomaker; M.J. van der Laan 2013 Journal Article
A General Implementation of TMLE for Longitudinal Data Applied to Causal Inference in Survival Analysis Ori M. Stitelman; Victor De Gruttola; Mark J. van der Laan 2012 Journal Article
Diagnosing and responding to violations in the positivity assumption Petersen ML, Porter KE, Gruber S, Wang Y, van der Laan MJ. 2012 Journal Article