Publications

Title Author Year Publication type
Dynamic Impact of Transfusion Ratios on Outcomes in Severely Injured Patients: Targeted Machine Learning Analysis of the Pragmatic, Randomized Optimal Platelet and Plasma Ratios Randomized Clinical Trial Nguyen, M.; Pirracchio, R.; Kornblith, L. Z.; Callcut, R.; Fox, E. E; Wade, C. E.; Schreiber, M.; Holcomb, J. B.; Coyle, J.; Cohen, M.; Hubbard, A. E. 2020 Journal Article
Estimators for the value of the optimal dynamic treatment rule with application to criminal justice interventions Montoya LM, van der Laan MJ, Skeem JL, Petersen ML. 2022 Journal Article
SSRI use during acute COVID-19 and risk of Long COVID among patients with depression Zachary Butzin-Dozier; Yunwen Ji; Sarang Deshpande; Eric Hurwitz; A. Jerrod Anzalone; Andrew Mertens, Ph.D.; Mark van der Laan, Ph.D. 2024 Journal Article
Empirical Efficiency Maximization: Improved Locally Efficient Covariate Adjustment in Randomized Experiments and Survival Analysis D. Rubin; M.J. van der Laan 2008 Journal Article
Depressive symptoms in low-income women in rural Mexico Fleischer, Nancy L.; Fernald, Lia C.; Hubbard, Alan E. 2007 Journal Article
Adaptive selection of the optimal strategy to improve precision and power in randomized trials Laura Balzer; Erica Cai; Lucas Godoy Garraza; Pracheta Amaranath 2024 Journal Article
Review 1: "Leveraging Pre-Vaccination Antibody Titers across Multiple Influenza H3N2 Variants to Forecast the Post-Vaccination Response" Zach Butzin-Dozier, Ph.D. 2024 Journal Article
Targeted learning of the mean outcome under an optimal dynamic treatment rule M. J. van der Laan; A. R. Luedtke 2014 Journal Article
Improved Small-Sample Estimation of Nonlinear Cross-Validated Prediction Metrics Benkeser D, Petersen M & van der Laan MJ 2019 Journal Article
Predicting Long COVID in the National COVID Cohort Collaborative Using Super Learner: Cohort Study Zach Butzin-Dozier, Ph.D.; Yunwen Ji; Haodong Li; Jeremy Coyle; Seraphina Shi; Rachael Phillips, Ph.D.; Andrew Mertens; Romain Pirracchio, M.D., MPH, Ph.D, FCCM; Mark van der Laan, Ph.D.; Rena C Patel; John M Colford; Alan Hubbard, Ph.D. 2024 Journal Article
Estimation and Evaluation of the Resource-Constrained Optimal Dynamic Treatment Rule: An Application to HIV Care Retention Lina M. Montoya; Maya Petersen, M.D. Ph.D. 2025 Journal Article
Countering the Curse of Dimensionality: Exploring Data-generating Mechanisms Through Participant Observation and Mechanistic Modeling; Epidemiology Hubbard, Alan; Trostle, James; Trostle, James; Cangemi, Ivan; Eisenberg, Joseph N. S 2020 Journal Article
Who is most at risk of dying if infected with SARS-CoV-2? A mortality risk factor analysis using machine learning of patients with COVID-19 over time: a large population-based cohort study in Mexico Lauren D Liao, Alan E Hubbard, Juan Pablo Gutierrez, Arturo Juárez-Flores, Kendall Kikkawa, Ronit Gupta, Yana Yarmolich, Iván de Jesús Ascencio-Montiel, Stefano M Bertozzi 2023 Journal Article
Highly Adaptive Ridge Mark van der Laan; Alexander Hagemeister; Alejandro Schuler, Ph.D. 2024 Journal Article
Targeted Maximum Likelihood Based Causal Inference Part I M.J. van der Laan 2010 Journal Article
Quantile-function based null distribution in resampling based multiple testing van der Laan, Mark J.; Hubbard, Alan E. 2006 Journal Article
When exposure affects subgroup membership: Framing relevant causal questions in perinatal epidemiology and beyond Shalika Gupta; Laura Balzer; Moses R Kamya; Diane V Havlir; Maya Petersen 2024 Journal Article
Highly Adaptive LASSO: Machine Learning that Provides Valid Nonparametric Inference in Realistic Models Zach Butzin-Dozier, Ph.D.; Sky Qiu; Alan Hubbard, Ph.D.; Seraphina Shi; Mark van der Laan, Ph.D. 2024 Journal Article
Statistical inference for the mean outcome under a possibly non-unique optimal treatment strategy A. R. Luedtke; M. J. van der Laan 2019 Journal Article
Machine learning to identify persons at high-risk of HIV acquisition in rural Kenya and Uganda Balzer LB, Havlir DV, Kamya MR, Chamie G, Charlebois ED, Clark TD, Koss CA, Kwarisiima D, Ayieko J, Sang N, Kabami J, Atukunda M, Jain V, Camlin CS, Cohen CR, Bukusi EA, van der Laan M, Petersen ML. 2020 Journal Article
Adaptive-TMLE for the Average Treatment Effect based on Randomized Controlled Trial Augmented with Real-World Data Mark van der Laan; Sky Qiu; Lars van der Laan 2024 Journal Article
Maternal experience of intimate partner violence, maternal depression, and parental stress are not associated with child telomere length in Bangladesh Diego Figueroa; Zach Butzin-Dozier, Ph.D.; Andrew Mertens, Ph.D.; Alan Hubbard, Ph.D. 2025 Journal Article
Big data and targeted machine learning in action to assist medical decision in the ICU; Anesthesia Critical Care \& Pain Medicine Pirracchio, Romain; Cohen, Mitchell J.; Malenica, Ivana; Cohen, Jonathan; Chambaz, Antoine; Cannesson, Maxime; Lee, Christine; Resche-Rigon, Matthieu; Hubbard, Alan E. 2019 Journal Article
Causes and Consequences of Child Growth Faltering in Low-resource settings Andrew Mertens, Jade Benjamin-Chung, John M. Colford Jr, Jeremy Coyle, Mark J. van der Laan, Alan E. Hubbard, Sonali Rosete, Ivana Malenica, Nima Hejazi, Oleg Sofrygin, Wilson Cai, Haodong Li, etc. 2023 Journal Article
Pathways through which water, sanitation, hygiene, and nutrition interventions reduce antibiotic use in young children: a mediation analysis of a cluster-randomized trial Anna Nguyen; Gabby Barratt Heitmann; Andrew Mertens, Ph.D.; Sania Ashraf; Md Ziaur Rahman; Shahjahan Ali; Mahbub Rahman; Benjamin F. Arnold; Jessica A. Grembi; Audrie Lin; Ayse Ercumen; Jade Benjamin-Chung 2024 Journal Article
Targeted Maximum Likelihood Based Causal Inference Part II M.J. van der Laan 2010 Journal Article
Mass extinctions as statistical phenomena: an examination of the evidence using chi-square tests and bootstrapping Hubbard, Alan E.; Gilinsky, Norman L. 1992 Journal Article
Estimating the effect of realistic improvements of metformin adherence on COVID-19 mortality using targeted machine learning Sky Qiu; Alan Hubbard; Juan Pablo Gutiérrez; Ganesh Pimpale; Arturo Juárez-Flores; Rakesh Ghosh; Iván de Jesús Ascencio-Montiel; Stefano M Bertozzi 2024 Journal Article
A Multi-Component Integrated HIV and Hypertension Care Model Improves Hypertension Screening and Control in Rural Uganda: A Cluster Randomized Trial Jane Kabami; Laura Balzer, Ph.D.; Mucunguzi Atukunda; Elizabeth Arinaitwe; Gerald Mutungi 2024 Journal Article
Optimal Individualized Treatments in Resource-Limited Settings A. Luedtke; M. van der Laan 2018 Journal Article
Super learner analysis of real-time electronically monitored adherence to antiretroviral therapy under constrained optimization and comparison to non-differentiated care approaches for persons living with HIV in rural Uganda †Benitez AE, Musinguzi N, Bangsberg DR, Bwana MB, Muzoora C, Hunt PW, Martin JN, Haberer JE, Petersen ML 2020 Journal Article
Implicit bias in Critical Care Data: Factors affecting sampling frequencies and missingness patterns of clinical and biological variables in ICU Patients Seraphina Shi; Alan Hubbard; Nicholas Fong; Romain Pirracchio 2024 Journal Article
Deep Causal Behavioral Policy Learning: Applications to Healthcare Jonas Knecht; Maya Petersen, M.D. Ph.D. 2025 Journal Article
A roadmap for estimating and interpreting population intervention parameters Ahern J, Hubbard A. 2009 Journal Article
A Causal Roadmap for Generating High-Quality Real-World Evidence Lauren E Dang , Susan Gruber , Hana Lee , Issa J Dahabreh , Elizabeth A Stuart , Brian D Williamson , Richard Wyss , Iván Dí 2023 Journal Article
Unlocking the potential of wearable device wear time to enhance postpartum depression screening and detection Eric Hurwitz; Samantha Meltzer-Brody; Zachary Butzin-Dozier; Rena C. Patel; Noémie Elhadad; Melissa A. Haendel 2024 Journal Article
A General Implementation of TMLE for Longitudinal Data Applied to Causal Inference in Survival Analysis Ori M. Stitelman; Victor De Gruttola; Mark J. van der Laan 2012 Journal Article
Targeted estimation and inference for the sample average treatment effect in trials with and without pair matching †Balzer, L; Petersen, M; van der Laan, M; the SEARCH Collaboration 2016 Journal Article
Is detection of enteropathogens and human or animal faecal markers in the environment associated with subsequent child enteric infections and growth: an individual participant data meta-analysis Andrew Mertens; Benjamin F Arnold; Jade Benjamin-Chung; Alexandria B Boehm; Joe Brown; Drew Capone; Thomas Clasen; Erica R Fuhrmeister; Jessica A Grembi; David Holcomb; Jackie Knee; Laura H Kwong; Audrie Lin; Stephen P Luby; Rassul Nala; Kara Nelson; Sammy M Njenga; Clair Null; Amy J Pickering; Mahbubur Rahman; Heather E Resse; Lauren Steinbaum; Jill R Stewart; Ruwan Thilakaratne; Oliver Cumming; John M Colford; Ayse Ercumen 2024 Journal Article
Technical Note: Targeted Maximum Likelihood Estimator for an ATE Standardized for New Target Population Mark van der Laan, Ph.D.; Susan Gruber 2025 Journal Article
Longitudinal Mediation Analysis with Time-varying Mediators and Exposures, with Application to Survival Outcomes W. Zheng; M. van der Laan 2017 Journal Article
Causal models and learning from data: integrating causal modeling and statistical estimation Petersen ML, van der Laan MJ 2014 Journal Article
Can drinking water, sanitation, handwashing, and nutritional interventions reduce antibiotic use in young children? Ayse Ercumen; Andrew Mertens; Zachary Butzin-Dozier; Da Kyung Jung; Shahjahan Ali; Beryl S. Achando; Gouthami Rao; Caitlin Hemlock; Amy J. Pickering; Christine P. Stewart; Sophia T. Tan; Jessica A. Grembi; Jade Benjamin-Chung; Marlene Wolfe; Gene G. Ho; Md. Ziaur Rahman; Charles D. Arnold; Holly N. Dentz; Sammy M Njenga; Dorie Meerkerk; Belinda Chen; Maya Nadimpalli; Mohammad Aminul Islam; Alan Hubbard; Clair Null; Leanne Unicomb; Mahbubur Rahman; John M. Colford Jr; Stephen P. Luby; Benjamin F. Arnold; Audrie Lin 2024 Journal Article
The impact of job stability on monetary poverty in Italy: causal small area estimation Katarzyna Reluga; Mark van der Laan, Ph.D. 2025 Journal Article
Big Data, Small Sample: Edgeworth Expansions Provide a Cautionary Tale Gerlovina, Inna; van der Laan, Mark J; Hubbard, Alan 2017 Journal Article
An Application of the Causal Roadmap in Two Safety Monitoring Case Studies: Causal Inference and Outcome Prediction using Electronic Health Record Data Brian D Williamson,Richard Wyss, Elizabeth A Stuart, Lauren E Dang, Andrew N Mertens, Romain S Neugebauer, Andrew Wilson, Susan Gruber 2023 Journal Article
Estimating conditional hazard functions and densities with the highly-adaptive lasso Anders Munch; Thomas A. Gerds; Mark van der Laan, Ph.D.; Helene C. W. Rytgaard 2024 Journal Article
Targeted Minimum Loss Based Estimation of Marginal Structural Working Models M. Petersen; J. Schwab; S. Gruber; N. Blaser; M. Schomaker; M.J. van der Laan 2013 Journal Article
Adaptive pre-specification in randomized trials with and without pair-matching Balzer, LB; van der Laan, MJ; Petersen, ML; SEARCH Collaboration 2016 Journal Article
Targeted Learning: Toward a Future Informed by Real-World Evidence Mark van der Laan; Rachael Phillips; Susan Gruber; Martin Ho; John Concato; Hana Lee 2023 Journal Article